In order for dapoxetine to work, is very important that you follow these guidelines so all the advantages of it be best achieved but reducing side effects as much as possible. Main outcome measures : Dapoxetine is used primarily in the treatment of premature ejaculation; it has been confirmed as effective for this indication by large-scale clinical trials. For example, it is reported that around 60% of men have more than a doubling in their intravaginal ejaculatory latency time (IELT), when taking dapoxetine versus placebo.
The prescribed dose of dapoxetine is ultimately 30 mg, taken a single to three hours previous and expected sexual action. Research that supports the efficacy of this timing suggests that when it comes to effectiveness, dapoxetine works best in patients who take meaningfull drug within a three hour window before last week. Exceeding the recommended dosage does not produce better results and it increases the risk of side effects, such as nausea, dizziness or headaches.
Dapoxetine therapy should be on demand according to clinical guidelines, not daily. It has advantages like it leads to less tolerance and allows the drug remain therapeutic. To preserve the pharmacokinetic attributes of dapoxetine, it is recommended in its summary product characteristics to be used intermittently such as 2–3 h before sexual activity[11].
Introduction Patients considering dapoxetine should know that this drug is contraindicated in individuals with some medical conditions (eg, severe liver impairment or use of monoamine oxidase inhibitors). These circumstances are able to increase unwanted side effects and also decrease the effectiveness of medicine. Likewise, under the guidelines of that manufacturer details not to use alcohol and recreational drugs because dapoxetine can act as a depressant on serotonin.*[2]
However, in practice several patients say that they get better sexual satisfaction and improved quality of relationship during correct use of dapoxetine. A Journal of Sexual Medicine survey revealed that 70% of men taking dapoxetine believed their sexual relationships were significantly influenced by something they could link to the number on a calendar, leading to enhanced relationship satisfaction.
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